Clozapine Center of Excellence

Education, resources, and tools to help you understand and optimize the use of clozapine

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Welcome to the Clozapine Center of Excellence (COE)

The Clozapine CoE helps clinicians and providers understand the safe and effective use of clozapine. It offers high-quality education, clinical consultations, interactive tools, vetted resources, and more.

  • Live and on-demand webinars
  • On-demand clinical consultations
  • Intensive consultations to clinics, practices, and health systems
  • Clinical tips and resources

For individual and family resources on LAIs, visit Resources for Individuals & Families

Some information presented within this Center of Excellence was created in collaboration with the California Department of State Hospitals (DSH). This includes that the content has been specifically aligned to the DSH’s medication guidelines (DSH Psychotropic Medication Operational Procedures, appended to DSH Policy Directive 3400). These medication guidelines are applicable only to the DSH settings and inclusion within this resource does not indicate that they must be followed in any non-DSH settings. The medication guidelines included in this Center are those of DSH and do not necessarily represent the views, policy(ies), and/or position(s) of the American Psychiatric Association (APA).

  • Resources
  • Education
  • Consultation
The American Psychiatric Association Guideline for Treatment of Patients with Schizophrenia

Maximizing Treatment Success for Patients with SMI: Promoting Adherence and Treatment Engagement

Using Motivational Interviewing with Serious Mental illness to Address Medication Non-Adherence, Create Change and Enhance Stability

Get Expert Guidance on Questions Around Clozapine

Submit any questions you have on managing side effects, assessment and monitoring, medical comorbidities, and any other topic. Receive a response within one business day from one of our national experts.

Can clozapine cause urinary retention, and if so, what can be done about it?
Is clozapine contraindicated for breastfeeding mothers?
Can clozapine cause blurry vision, and if so what can be done about this?

Trending Topics

Use our Resources page to find evidence-based answers and resources on clozapine. Here are some popular topics — all vetted by our Clinical Expert Team.

Video: First-line Treatments for Clozapine-induced Drooling

Drooling (sialorrhea) is one of the most common side effects…

Indications for Taking Clozapine

A substantial proportion of people with schizophrenia do not respond…

Indications & Use

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Specific Medical/Hematological Issues

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Dosing, Transitioning & Treatment Response

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Side Effect Management

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Information for Individuals & Families

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