LAI Conversion Tool
This tool is designed to provide dosing recommendations for initial and maintenance doses of LAI based on an oral dose of antipsychotic medication. Loading doses are recommended for some medications to reduce the time to steady-state plasma levels from months to weeks. Dosing should be adjusted using measurement of trough antipsychotic plasma levels, measured 1-3 days prior to the next maintenance dose.
Oral tolerability with all medications should be verified prior to consideration of an LAI.
Select the desired oral medication and desired oral dose that the patient is receiving. The LAI dosing recommendations will populate with links to additional tips on the corresponding LAI.
Information presented within this tool was created in collaboration with the California Department of State Hospitals (DSH). This includes that the content has been specifically aligned to the DSH’s medication guidelines (DSH Psychotropic Medication Operational Procedures, appended to DSH Policy Directive 3400). These medication guidelines are applicable only to the DSH settings and inclusion within this resource does not indicate that they must be followed in any non-DSH settings. The medication guidelines included in this resource are those of DSH and do not necessarily represent the views, policy(ies), and/or position(s) of the American Psychiatric Association (APA).