Mistakes People Make with LAIs

Free
Oct 16th, 2025
12:00 pm to 1:00 pm PST
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This presentation will focus on common errors and best practices when using long-acting injectable antipsychotics (LAIs). Key topics covered include: LAI Kinetics: The importance of understanding the kinetics of different LAI agents and which ones require loading injections or oral coverage. Combination Treatment: Detailed guidance on which oral or injectable agents can be combined. The presentation emphasizes that partial agonists like LAI aripiprazole have high D2 receptor affinity and should not be used in combination with other D2 antagonist LAIs. Specific Recommendations: For LAI aripiprazole, the presentation suggests adding oral xanomeline-trospium (XT) or clozapine. For other agents like LAI risperidone or paliperidone, it advises against combination LAIs and instead suggests either a dose increase of the oral agent or adding XT or clozapine. First-Generation Antipsychotics (FGAs): The presentation highlights that FGAs, such as haloperidol decanoate, still have a role in treatment and provides a simple conversion formula from oral to injectable doses. 

Oct 16th, 2025
Free
On Demand
Psychopharmacology Interventions
1 CME
1 Pharmacy (CPE)
1 Nursing (NCPD)
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